TY - JOUR
T1 - Progress in realizing the promise of microarrays in systems neurobiology
AU - Dougherty, Joseph D.
AU - Geschwind, Daniel H.
PY - 2005/1/20
Y1 - 2005/1/20
N2 - The power of microarrays in neuroscience has been challenged by the cellular heterogeneity and complexity of the central nervous system. In this issue of Neuron, Arlotta, Molyneaux, and colleagues have developed a technique combining retrograde labeling, flow cytometry, and microarrays to purify and molecularly characterize a specific population of neurons from the brain, focusing here on cortical projection neurons. We discuss these findings and the implications of this development for both systems and molecular neuroscience.
AB - The power of microarrays in neuroscience has been challenged by the cellular heterogeneity and complexity of the central nervous system. In this issue of Neuron, Arlotta, Molyneaux, and colleagues have developed a technique combining retrograde labeling, flow cytometry, and microarrays to purify and molecularly characterize a specific population of neurons from the brain, focusing here on cortical projection neurons. We discuss these findings and the implications of this development for both systems and molecular neuroscience.
UR - http://www.scopus.com/inward/record.url?scp=12344336772&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2005.01.007
DO - 10.1016/j.neuron.2005.01.007
M3 - Review article
C2 - 15664168
AN - SCOPUS:12344336772
SN - 0896-6273
VL - 45
SP - 183
EP - 185
JO - Neuron
JF - Neuron
IS - 2
ER -