TY - JOUR
T1 - Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients
T2 - Reversibility of the early metabolite abnormalities relates with a good outcome
AU - Aragão, Maria De Fátima Viana Vasco
AU - Law, Meng
AU - Netto, João Prola
AU - Valença, Marcelo Moraes
AU - Naidich, Thomas
PY - 2009/3
Y1 - 2009/3
N2 - In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (1H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) 1H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early 1H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.
AB - In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (1H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) 1H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early 1H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.
KW - Hypoxia
KW - Magnetic resonance spectroscopy
KW - Near drowning
UR - http://www.scopus.com/inward/record.url?scp=66149175285&partnerID=8YFLogxK
U2 - 10.1590/S0004-282X2009000100014
DO - 10.1590/S0004-282X2009000100014
M3 - Article
C2 - 19330212
AN - SCOPUS:66149175285
SN - 0004-282X
VL - 67
SP - 55
EP - 57
JO - Arquivos de Neuro-Psiquiatria
JF - Arquivos de Neuro-Psiquiatria
IS - 1
ER -