Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure

Chim C. Lang; Piergiuseppe Agostoni; Donna M. Mancini

doi:10.1016/j.cardfail.2007.05.004

Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure

Chim C. Lang
, Piergiuseppe Agostoni
, Donna M. Mancini

Research output: Contribution to journal › Review article › peer-review

66 Scopus citations

Abstract

The peak VO₂ is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO₂ may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO₂. Several groups have looked at exercise-derived variables beyond peak VO₂ to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO₂ in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.

Original language	English
Pages (from-to)	672-679
Number of pages	8
Journal	Journal of Cardiac Failure
Volume	13
Issue number	8
DOIs	https://doi.org/10.1016/j.cardfail.2007.05.004
State	Published - Oct 2007
Externally published	Yes

Keywords

Chronic heart failure
cardiac output
cardiac transplantation
exercise

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10.1016/j.cardfail.2007.05.004

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title = "Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure",

abstract = "The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2. Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.",

keywords = "Chronic heart failure, cardiac output, cardiac transplantation, exercise",

author = "Lang, \{Chim C.\} and Piergiuseppe Agostoni and Mancini, \{Donna M.\}",

year = "2007",

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language = "English",

volume = "13",

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TY - JOUR

T1 - Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure

AU - Lang, Chim C.

AU - Agostoni, Piergiuseppe

AU - Mancini, Donna M.

PY - 2007/10

Y1 - 2007/10

N2 - The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2. Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.

AB - The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2. Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.

KW - Chronic heart failure

KW - cardiac output

KW - cardiac transplantation

KW - exercise

UR - https://www.scopus.com/pages/publications/34948820166

U2 - 10.1016/j.cardfail.2007.05.004

DO - 10.1016/j.cardfail.2007.05.004

M3 - Review article

C2 - 17923361

AN - SCOPUS:34948820166

SN - 1071-9164

VL - 13

SP - 672

EP - 679

JO - Journal of Cardiac Failure

JF - Journal of Cardiac Failure

IS - 8

ER -

Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure

Abstract

Keywords

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