TY - JOUR
T1 - Prognostic Significance and Measurement of Exercise-Derived Hemodynamic Variables in Patients With Heart Failure
AU - Lang, Chim C.
AU - Agostoni, Piergiuseppe
AU - Mancini, Donna M.
PY - 2007/10
Y1 - 2007/10
N2 - The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2. Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.
AB - The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2. Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.
KW - Chronic heart failure
KW - cardiac output
KW - cardiac transplantation
KW - exercise
UR - http://www.scopus.com/inward/record.url?scp=34948820166&partnerID=8YFLogxK
U2 - 10.1016/j.cardfail.2007.05.004
DO - 10.1016/j.cardfail.2007.05.004
M3 - Review article
C2 - 17923361
AN - SCOPUS:34948820166
SN - 1071-9164
VL - 13
SP - 672
EP - 679
JO - Journal of Cardiac Failure
JF - Journal of Cardiac Failure
IS - 8
ER -