Prognosis of fetuses with a cystic hygroma

Harold S. Bernstein, Roy A. Filly, James D. Goldberg, Mitchell S. Golbus

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69 Scopus citations


This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.

Original languageEnglish
Pages (from-to)349-355
Number of pages7
JournalPrenatal Diagnosis
Issue number6
StatePublished - Jun 1991
Externally publishedYes


  • Cystic hygroma
  • Fetal aneuploidy
  • Non‐immune hydrops
  • Septation


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