Prognosis of fetuses with a cystic hygroma

Harold S. Bernstein; Roy A. Filly; James D. Goldberg; Mitchell S. Golbus

doi:10.1002/pd.1970110603

Prognosis of fetuses with a cystic hygroma

Harold S. Bernstein, Roy A. Filly, James D. Goldberg, Mitchell S. Golbus

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.

Original language	English
Pages (from-to)	349-355
Number of pages	7
Journal	Prenatal Diagnosis
Volume	11
Issue number	6
DOIs	https://doi.org/10.1002/pd.1970110603
State	Published - Jun 1991
Externally published	Yes

Keywords

Cystic hygroma
Fetal aneuploidy
Non‐immune hydrops
Septation

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title = "Prognosis of fetuses with a cystic hygroma",

abstract = "This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.",

keywords = "Cystic hygroma, Fetal aneuploidy, Non‐immune hydrops, Septation",

author = "Bernstein, {Harold S.} and Filly, {Roy A.} and Goldberg, {James D.} and Golbus, {Mitchell S.}",

year = "1991",

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AU - Bernstein, Harold S.

AU - Filly, Roy A.

AU - Goldberg, James D.

AU - Golbus, Mitchell S.

PY - 1991/6

Y1 - 1991/6

N2 - This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.

AB - This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.

KW - Cystic hygroma

KW - Fetal aneuploidy

KW - Non‐immune hydrops

KW - Septation

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SP - 349

EP - 355

JO - Prenatal Diagnosis

JF - Prenatal Diagnosis

IS - 6

ER -

Prognosis of fetuses with a cystic hygroma

Abstract

Keywords

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