Profilechaser: Searching microarray repositories based on genome-wide patterns of differential expression

Jesse M. Engreitz; Rong Chen; Alexander A. Morgan; Joel T. Dudley; Rohan Mallelwar; Atul J. Butte

doi:10.1093/bioinformatics/btr548

Profilechaser: Searching microarray repositories based on genome-wide patterns of differential expression

Jesse M. Engreitz, Rong Chen, Alexander A. Morgan, Joel T. Dudley, Rohan Mallelwar, Atul J. Butte

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

We introduce ProfileChaser, a web server that allows for querying the Gene Expression Omnibus based on genome-wide patterns of differential expression. Using a novel, content-based approach, ProfileChaser retrieves expression profiles that match the differentially regulated transcriptional programs in a user-supplied experiment. This analysis identifies statistical links to similar expression experiments from the vast array of publicly available data on diseases, drugs, phenotypes and other experimental conditions.

Original language	English
Article number	btr548
Pages (from-to)	3317-3318
Number of pages	2
Journal	Bioinformatics
Volume	27
Issue number	23
DOIs	https://doi.org/10.1093/bioinformatics/btr548
State	Published - Dec 2011
Externally published	Yes

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10.1093/bioinformatics/btr548

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Profilechaser: Searching microarray repositories based on genome-wide patterns of differential expression

Abstract

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