Production of Influenza Virus Glycoproteins Using Insect Cells

Madhumathi Loganathan, Benjamin Francis, Florian Krammer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The baculovirus/insect cell expression system is a very useful tool for reagent and antigen generation in vaccinology, virology, and immunology. It allows for the production of recombinant glycoproteins, which are used as antigens in vaccination studies and as reagents in immunological assays. Here, we describe the process of recombinant glycoprotein production using the baculovirus/insect cell expression system.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages43-70
Number of pages28
DOIs
StatePublished - 2024

Publication series

NameMethods in Molecular Biology
Volume2762
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Baculovirus
  • Hemagglutinin
  • Influenza virus
  • Insect cells
  • Neuraminidase
  • Protein production
  • Viral glycoproteins

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