TY - JOUR
T1 - Processed meat consumption and risk of cancer
T2 - A multisite casecontrol study in Uruguay
AU - De Stefani, E.
AU - Boffetta, P.
AU - Ronco, A. L.
AU - Deneo-Pellegrini, H.
AU - Correa, P.
AU - Acosta, G.
AU - Mendilaharsu, M.
AU - Luaces, M. E.
AU - Silva, C.
N1 - Funding Information:
The present study was funded by the International Agency for Research on Cancer, Lyon, France. This work was supported by a grant from International Agency for Research on Cancer, Lyon, France.
PY - 2012/10/23
Y1 - 2012/10/23
N2 - Background: The role of processed meat in the aetiology of several cancers was explored in detail. Methods: In the time period 19962004, a multisite casecontrol study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity, pharynx, oesophagus, stomach, colon, rectum, larynx, lung, female breast, prostate, urinary bladder, and kidney (renal cell carcinoma only). Results: The highest odds ratios (ORs) were positively associated with cancers of the colon, rectum, stomach, oesophagus, and lung. With the exception of renal cell carcinoma, the remaining cancer sites were significantly associated with elevated risks for processed meat consumption. Furthermore, mortadella, salami, hot dog, ham, and salted meat were strongly associated with risk of several cancer sites. Conclusion: It could be concluded that processed meat intake could be a powerful multiorgan carcinogen.
AB - Background: The role of processed meat in the aetiology of several cancers was explored in detail. Methods: In the time period 19962004, a multisite casecontrol study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity, pharynx, oesophagus, stomach, colon, rectum, larynx, lung, female breast, prostate, urinary bladder, and kidney (renal cell carcinoma only). Results: The highest odds ratios (ORs) were positively associated with cancers of the colon, rectum, stomach, oesophagus, and lung. With the exception of renal cell carcinoma, the remaining cancer sites were significantly associated with elevated risks for processed meat consumption. Furthermore, mortadella, salami, hot dog, ham, and salted meat were strongly associated with risk of several cancer sites. Conclusion: It could be concluded that processed meat intake could be a powerful multiorgan carcinogen.
KW - breast cancer
KW - colorectal cancer
KW - gastric cancer
KW - lung cancer
KW - oesophageal cancer
KW - prostate cancer
UR - http://www.scopus.com/inward/record.url?scp=84867899357&partnerID=8YFLogxK
U2 - 10.1038/bjc.2012.433
DO - 10.1038/bjc.2012.433
M3 - Article
C2 - 23011480
AN - SCOPUS:84867899357
SN - 0007-0920
VL - 107
SP - 1584
EP - 1588
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 9
ER -