Priority Should be Given to Centers that Split En Bloc Pediatric Kidneys to Maximize Transplantation: A Single Center Experience

  • Daniel Barbash
  • , Miriam Steinberger
  • , Julia Torabi
  • , Hillary Yaffe
  • , Maria Ajaimy
  • , Enver Akalin
  • , Luz E. Liriano
  • , Yorg Azzi
  • , Swati Jain
  • , Cindy Pynadath
  • , Nidal Muhdi
  • , Marie Le
  • , Jay A. Graham

Research output: Contribution to journalArticlepeer-review

Abstract

The foundation for OPTN policy 8.5.B that allows for en bloc kidney utilization from pediatric donors under <18 kg is unclear. Naturally, kidneys recovered from these donors can be split and transplanted into 2 adult recipients as opposed to only 1 (OPTN policy 8.5.C). Our center universally splits all pediatric donor kidneys. We showed that early eGFR is lower in recipients that receive a kidney from a donor <18 kg (3-month eGFR; 36.3 vs 49.7 mL/min/1.73 m2, P = .01), but quickly rebounds with no significant differences thereafter. As such, efforts should be made to revisit the practice of en bloc kidney transplantation from small pediatric donors. Given similar complication rates and outcomes seen at our center between the 2 groups, “splitting first” should be the policy to ensure maximalization of transplant recipients.

Original languageEnglish
Pages (from-to)250-254
Number of pages5
JournalTransplantation Proceedings
Volume57
Issue number2
DOIs
StatePublished - Mar 2025
Externally publishedYes

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