TY - JOUR
T1 - Primitive neuroectodermal tumor cell lines
T2 - Chromosomal analysis of five cases
AU - Potluri, Venkateswara R.
AU - Gilbert, Fred
AU - Helsen, Christiane
AU - Helson, Lawrence
PY - 1987/1
Y1 - 1987/1
N2 - A cytogenetic analysis of primitive neuroectodermal tumor (PNET) cell lines was undertaken. PNET are presumed to be embryologically related to, but clinically and histologically distinct from, other tumors of neuroectodermal origin, including neuroblastoma and retinoblastoma. No single chromosome abnormality was found in all five of the tumors studied. In three of the five cases, however, additional 1q material [either as extra chromosome #1 or i(1q)] was found in all cells, and in two of the five, monosomy 13 was noted in all cells; the possible significance of these findings is discussed.
AB - A cytogenetic analysis of primitive neuroectodermal tumor (PNET) cell lines was undertaken. PNET are presumed to be embryologically related to, but clinically and histologically distinct from, other tumors of neuroectodermal origin, including neuroblastoma and retinoblastoma. No single chromosome abnormality was found in all five of the tumors studied. In three of the five cases, however, additional 1q material [either as extra chromosome #1 or i(1q)] was found in all cells, and in two of the five, monosomy 13 was noted in all cells; the possible significance of these findings is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0023232989&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(87)90084-7
DO - 10.1016/0165-4608(87)90084-7
M3 - Article
C2 - 3024811
AN - SCOPUS:0023232989
SN - 0165-4608
VL - 24
SP - 75
EP - 86
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -