Primary malignant melanoma of the esophagus

Axel W. Joob, G. Kenneth Haines, Merrill S. Kies, Thomas W. Shields

Research output: Contribution to journalArticlepeer-review

90 Scopus citations


Primary malignant melanoma of the esophagus is a rare disease. A case is reported and the newer diagnostic techniques of immunohistologic identification of the tumor by positive reaction to the HMB-45 antigen, as well as immunoscintigraphy with Technetium-99m-labeled melanoma monoclonal antigen for the demonstration of distant metastasis, is presented. A current review of the literature on this uncommon tumor is presented, and treatment options are discussed. A total esophagectomy remains the treatment of choice. Four long-term (>5 years) survivors after adequate surgical removal have been recorded in the literature.

Original languageEnglish
Pages (from-to)217-222
Number of pages6
JournalAnnals of Thoracic Surgery
Issue number1
StatePublished - Jul 1995
Externally publishedYes


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