Primary dural mucosa-associated lymphoid tissue-type lymphoma: Case report and review of the literature

M. Rottnek, J. Strauchen, F. Moore, Susan Morgello

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

A 47-year-old Hispanic male presented with visual field disturbances, memory impairment, and a seizure. CT and MRI were consistent with meningioma. Both neurologic exam and routine laboratory tests were within normal limits. The patient underwent craniotomy and subtotal resection of the tumor. On H&E, the lesion was composed of a lymphoid mass with well-defined irregularly shaped follicles surrounded by a monomorphic population of small lymphocytes. Marginal zones stained for B-cell markers, CD20 and CD79a, one T-cell marker, CD43, and kappa light chains. While other markers did not stain the majority of tumor cells, they did identify other lymphoid and plasma cell elements. A diagnosis of marginal zone B-cell lymphoma of dura, mucosa-associated lymphoid tissue (MALT)-type (extranodal) was made. MALT-type lymphomas are unusual in the nervous system; this is the first such case reported in a male and serves to emphasize the wide diversity of presentation of a neoplasm originally described in the GI tract and thus far described in the CNS only in females.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalJournal of Neuro-Oncology
Volume68
Issue number1
DOIs
StatePublished - May 2004

Keywords

  • CNS MALToma
  • Dural lymphoma

Fingerprint

Dive into the research topics of 'Primary dural mucosa-associated lymphoid tissue-type lymphoma: Case report and review of the literature'. Together they form a unique fingerprint.

Cite this