Primary cutaneous Aspergillus fumigatus infection in immunocompetent host

Pradeep Kumar Mada, Daniel Alexander Saldaña Koppel, Majd Al Shaarani, Andrew Stevenson Joel Chandranesan

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery.

Original languageEnglish
Article number233020
JournalBMJ Case Reports
Volume13
Issue number2
DOIs
StatePublished - 13 Feb 2020
Externally publishedYes

Keywords

  • dermatological
  • drugs: infectious diseases
  • exposures
  • pathology
  • skin

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