TY - JOUR
T1 - Previous maternal infection with Toxoplasma gondii and the risk of fetal death
AU - Chen, Katherine T.
AU - Eskild, Anne
AU - Bresnahan, Michaeline
AU - Stray-Pedersen, Babill
AU - Sher, Arnold
AU - Jenum, Pål A.
N1 - Funding Information:
Supported in part by a Women's Reproductive Health Research Career Development Center grant from the National Institutes of Child Health and Human Development (to Dr Chen).
PY - 2005/8
Y1 - 2005/8
N2 - Objective: The purpose of this study was to assess the association between previous maternal Toxoplasma gondii (T gondii) infection and risk of fetal death. Study design: This was a population-based prospective cohort of 29,912 pregnant women without acute T gondii infection in Norway. Results: In the study population, 2937 (9.8%) women had evidence of previous maternal T gondii infection, and 299 (1.0%) had fetal deaths. We found no association between previous T gondii infection and risk of fetal death at ≥20 weeks of gestation. We did find a trend for an increased risk of fetal death at ≥16 and <20 weeks of gestation. However, we noted no association between previous T gondii infection and risk of fetal death at all birth weight categories (≥1000, ≥500 and <1000, and <500 g). Conclusion: These data do not indicate an increased risk of fetal death at ≥20 weeks of gestation in women with previous maternal T gondii infection.
AB - Objective: The purpose of this study was to assess the association between previous maternal Toxoplasma gondii (T gondii) infection and risk of fetal death. Study design: This was a population-based prospective cohort of 29,912 pregnant women without acute T gondii infection in Norway. Results: In the study population, 2937 (9.8%) women had evidence of previous maternal T gondii infection, and 299 (1.0%) had fetal deaths. We found no association between previous T gondii infection and risk of fetal death at ≥20 weeks of gestation. We did find a trend for an increased risk of fetal death at ≥16 and <20 weeks of gestation. However, we noted no association between previous T gondii infection and risk of fetal death at all birth weight categories (≥1000, ≥500 and <1000, and <500 g). Conclusion: These data do not indicate an increased risk of fetal death at ≥20 weeks of gestation in women with previous maternal T gondii infection.
KW - Complications
KW - Epidemiology
KW - Fetal death
KW - Toxoplasma gondii
UR - http://www.scopus.com/inward/record.url?scp=23844535367&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2004.12.016
DO - 10.1016/j.ajog.2004.12.016
M3 - Article
C2 - 16098868
AN - SCOPUS:23844535367
SN - 0002-9378
VL - 193
SP - 443
EP - 449
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 2
ER -