TY - JOUR
T1 - Prevention of Events with Angiotensin-Converting Enzyme Inhibition (The PEACE study design)
AU - Pfeffer, Marc A.
AU - Domanski, Michael
AU - Rosenberg, Yves
AU - Verter, Joel
AU - Geller, Nancy
AU - Albert, Paul
AU - Hsia, Judith
AU - Braunwald, Eugene
N1 - Funding Information:
PEACE is supported by a grant from the National Heart, Lung, and Blood Institute of the US National Institutes of Health; drug supply and distribution is provided by a grant from Knoll.
PY - 1998/8/6
Y1 - 1998/8/6
N2 - The Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) trial is an 8,100 patient, randomized, double-blind, placebo- controlled trial designed to determine the usefulness of angiotensin- converting enzyme (ACE) inhibitors in treating coronary patients with preserved left ventricular ejection fraction. The hypothesis being tested in this trial is that patients with coronary disease and ejection fraction ≤40% who are treated with ACE inhibitors will experience a reduction in the incidence of cardiovascular death, nonfatal myocardial infarction, or a revascularization procedure compared with patients treated with conventional therapy. The design of the PEACE trial is described herein.
AB - The Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) trial is an 8,100 patient, randomized, double-blind, placebo- controlled trial designed to determine the usefulness of angiotensin- converting enzyme (ACE) inhibitors in treating coronary patients with preserved left ventricular ejection fraction. The hypothesis being tested in this trial is that patients with coronary disease and ejection fraction ≤40% who are treated with ACE inhibitors will experience a reduction in the incidence of cardiovascular death, nonfatal myocardial infarction, or a revascularization procedure compared with patients treated with conventional therapy. The design of the PEACE trial is described herein.
UR - http://www.scopus.com/inward/record.url?scp=0031722541&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(98)00488-3
DO - 10.1016/S0002-9149(98)00488-3
M3 - Article
C2 - 9719019
AN - SCOPUS:0031722541
SN - 0002-9149
VL - 82
SP - 25
EP - 30
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 3 A
ER -