TY - JOUR
T1 - Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus infection in chronic kidney disease
T2 - Synopsis of the kidney disease: Improving global outcomes 2018 clinical practice guideline
AU - Gordon, Craig E.
AU - Berenguer, Marina C.
AU - Doss, Wahid
AU - Fabrizi, Fabrizio
AU - Izopet, Jacques
AU - Jha, Vivekanand
AU - Kamar, Nassim
AU - Kasiske, Bertram L.
AU - Lai, Ching Lung
AU - Morales, Jose M.
AU - Patel, Priti R.
AU - Pol, Stanislas
AU - Silva, Marcelo O.
AU - Balk, Ethan M.
AU - Earley, Amy
AU - Di, Mengyang
AU - Cheung, Michael
AU - Jadoul, Michel
AU - Martin, Paul
N1 - Publisher Copyright:
© 2019 American College of Physicians.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is an extensive update of KDIGO's 2008 guideline on HCV infection in CKD. This update reflects the major advances since the introduction of directacting antivirals (DAAs) in the management of HCV infection in the CKD population. Methods: The KDIGO work group tasked with developing the HCV and CKD guideline defined the scope of the guideline, gathered evidence, determined topics for systematic review, and graded the quality of evidence previously summarized by the evidence review team. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach was used to appraise the quality of evidence and rate the strength of the recommendations. Searches of the Englishlanguage literature were conducted through May 2017 and were supplemented with targeted searches for studies of DAA treatment and with abstracts from nephrology, hepatology, and transplantation conferences. A review process involving many stakeholders, subject matter experts, and industry and national organizations informed the guideline's final modification. Recommendation: The updated guideline comprises 66 recommendations. This synopsis focuses on 32 key recommendations pertinent to the prevention, diagnosis, treatment, and management of HCV infection in adult CKD populations.
AB - Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is an extensive update of KDIGO's 2008 guideline on HCV infection in CKD. This update reflects the major advances since the introduction of directacting antivirals (DAAs) in the management of HCV infection in the CKD population. Methods: The KDIGO work group tasked with developing the HCV and CKD guideline defined the scope of the guideline, gathered evidence, determined topics for systematic review, and graded the quality of evidence previously summarized by the evidence review team. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach was used to appraise the quality of evidence and rate the strength of the recommendations. Searches of the Englishlanguage literature were conducted through May 2017 and were supplemented with targeted searches for studies of DAA treatment and with abstracts from nephrology, hepatology, and transplantation conferences. A review process involving many stakeholders, subject matter experts, and industry and national organizations informed the guideline's final modification. Recommendation: The updated guideline comprises 66 recommendations. This synopsis focuses on 32 key recommendations pertinent to the prevention, diagnosis, treatment, and management of HCV infection in adult CKD populations.
UR - http://www.scopus.com/inward/record.url?scp=85072896762&partnerID=8YFLogxK
U2 - 10.7326/M19-1539
DO - 10.7326/M19-1539
M3 - Article
C2 - 31546256
AN - SCOPUS:85072896762
SN - 0003-4819
VL - 171
SP - 496
EP - 504
JO - Annals of Internal Medicine
JF - Annals of Internal Medicine
IS - 7
ER -