TY - JOUR
T1 - Prevalence of tic disorders
T2 - A systematic review and meta-analysis
AU - Knight, Tristan
AU - Steeves, Thomas
AU - Day, Lundy
AU - Lowerison, Mark
AU - Jette, Nathalie
AU - Pringsheim, Tamara
N1 - Funding Information:
The authors acknowledge Rosie Wartecker from the Tourette Syndrome Foundation of Canada for her review of the manuscript, and Diane Lorenzetti for her assistance with developing search strategies. Funding for this study was provided by the Public Health Agency of Canada. The opinions expressed in this review are those of the authors/researchers, and do not necessarily reflect the official views of the Public Health Agency of Canada. N.J. holds an Alberta Innovates Health Solutions Population Health Investigator Award and a Canada Research Chair in Neurological Population Health and Health Services Research.
PY - 2012/8
Y1 - 2012/8
N2 - This study evaluated the prevalence of tic disorders. MEDLINE and EMBASE databases were searched, using terms specific to Tourette syndrome and tic disorders, for studies of incidence, prevalence, and epidemiology. Thirty-five studies reporting data from 1985-2011 on the incidence or prevalence of tic disorders in a defined population were included. One reported incidence, and 34 reported prevalence. Meta-analysis of 13 studies of children yielded a prevalence of Tourette syndrome at 0.77% (95% confidence interval, 0.39-1.51%). Prevalence is higher in boys: 1.06% of boys were affected (95% confidence interval, 0.54-2.09%) vs 0.25% of girls (95% confidence interval, 0.05-1.20%). Transient tic disorder comprised the most common tic disorder in children, affecting 2.99% (95% confidence interval, 1.60-5.61%). Meta-analysis of two studies assessing adults for Tourette syndrome revealed a prevalence of 0.05% (95% confidence interval, 0.03-0.08%). The prevalence of tic disorders was higher in all studies performed in special education populations. Tic disorders are more common in children than adults, in boys than girls, and in special education populations. Parents, educators, healthcare professionals, and administrators should be aware of the frequency with which tic disorders occur, and ensure proper access to appropriate care.
AB - This study evaluated the prevalence of tic disorders. MEDLINE and EMBASE databases were searched, using terms specific to Tourette syndrome and tic disorders, for studies of incidence, prevalence, and epidemiology. Thirty-five studies reporting data from 1985-2011 on the incidence or prevalence of tic disorders in a defined population were included. One reported incidence, and 34 reported prevalence. Meta-analysis of 13 studies of children yielded a prevalence of Tourette syndrome at 0.77% (95% confidence interval, 0.39-1.51%). Prevalence is higher in boys: 1.06% of boys were affected (95% confidence interval, 0.54-2.09%) vs 0.25% of girls (95% confidence interval, 0.05-1.20%). Transient tic disorder comprised the most common tic disorder in children, affecting 2.99% (95% confidence interval, 1.60-5.61%). Meta-analysis of two studies assessing adults for Tourette syndrome revealed a prevalence of 0.05% (95% confidence interval, 0.03-0.08%). The prevalence of tic disorders was higher in all studies performed in special education populations. Tic disorders are more common in children than adults, in boys than girls, and in special education populations. Parents, educators, healthcare professionals, and administrators should be aware of the frequency with which tic disorders occur, and ensure proper access to appropriate care.
UR - http://www.scopus.com/inward/record.url?scp=84863323051&partnerID=8YFLogxK
U2 - 10.1016/j.pediatrneurol.2012.05.002
DO - 10.1016/j.pediatrneurol.2012.05.002
M3 - Review article
C2 - 22759682
AN - SCOPUS:84863323051
SN - 0887-8994
VL - 47
SP - 77
EP - 90
JO - Pediatric Neurology
JF - Pediatric Neurology
IS - 2
ER -