TY - JOUR
T1 - Prevalence of Age-related Macular Degeneration in Greece
T2 - The Thessaloniki Eye Study
AU - Topouzis, Fotis
AU - Coleman, Anne L.
AU - Harris, Alon
AU - Anastasopoulos, Eleftherios
AU - Yu, Fei
AU - Koskosas, Archimidis
AU - Pappas, Theofanis
AU - Mavroudis, Leonidas
AU - Wilson, M. Roy
N1 - Funding Information:
This study was supported in part by International Glaucoma Association, London, United Kingdom, UCLA Center for Eye Epidemiology, Los Angeles, California, Health Future Foundation, Creighton University, Omaha, Nebraska, Texas Tech University Health Sciences Center, Lubbock, Texas, Pfizer, Inc, New York, New York, Merck and Co, Inc, Whitehouse Station, New Jersey, Pharmacia Hellas, Athens, Greece, and Novartis Hellas, Athens, Greece. The authors indicate no financial conflict of interest. Involved in design and conduct of the study (F.T., A.L.C., A.H., M.R.W.); Involved in collection, management, analysis, and interpretation of the data (F.T., A.L.C., A.H., E.A., F.Y., A.K., T.P., L.M., M.R.W.); and involved in preparation, review, or approval of the manuscript (F.T., A.L.C., A.H., E.A., F.Y., A.K., T.P., L.M., M.R.W.).
PY - 2006/12
Y1 - 2006/12
N2 - Purpose: To estimate the age- and gender-specific prevalence of age-related macular degeneration (AMD) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: A total of 2554 subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Results: Of the 3617 eligible subjects, 2554 (71%) participants completed a clinical examination. The prevalence was 2.5% for AMD, 1.4% for neovascular (NV) AMD, and 1.3% for geographic atrophy (GA). Bilateral AMD was present in 40% of AMD cases. The prevalence of AMD, NV, GA, and bilateral AMD increased with increasing age (P< .0001). No gender-specific statistically significant differences were noted. Of all participants with AMD, 67% were unaware of the diagnosis. Conclusions: The prevalence of AMD in Greece is comparable to that in other Caucasian populations. A dramatic increase in prevalence in people older than 80 years of age was observed.
AB - Purpose: To estimate the age- and gender-specific prevalence of age-related macular degeneration (AMD) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: A total of 2554 subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Results: Of the 3617 eligible subjects, 2554 (71%) participants completed a clinical examination. The prevalence was 2.5% for AMD, 1.4% for neovascular (NV) AMD, and 1.3% for geographic atrophy (GA). Bilateral AMD was present in 40% of AMD cases. The prevalence of AMD, NV, GA, and bilateral AMD increased with increasing age (P< .0001). No gender-specific statistically significant differences were noted. Of all participants with AMD, 67% were unaware of the diagnosis. Conclusions: The prevalence of AMD in Greece is comparable to that in other Caucasian populations. A dramatic increase in prevalence in people older than 80 years of age was observed.
UR - http://www.scopus.com/inward/record.url?scp=33845229861&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2006.07.042
DO - 10.1016/j.ajo.2006.07.042
M3 - Article
C2 - 17157601
AN - SCOPUS:33845229861
SN - 0002-9394
VL - 142
SP - 1076
EP - 1079
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 6
ER -