The success of transplantation and replantation in recent years clearly establishes the fact that most tissues or organs in the body can tolerate a period of ischemia and survive after reestablishment of circulation. Extending this tolerable period of ischemia would be immediately useful in extending the scope of feasible clinical microvascular surgery. In the future, such technology would be an essential aspect of tissue banking technology. Experimental data and clinical experience with hypothermic preservation indicate that this tolerable warm ischemia time can be extended several-fold simply by cooling. Controversies remain regarding the role of perfusion, the ideal composition of the perfusate, and the optimal method of cooling. Bearing in mind the success of banks for red cell, skin, sperm, and other biologically active organisms, a certain amount of optimism seems justifiable.
|Number of pages||5|
|Journal||Clinics in Plastic Surgery|
|State||Published - 1983|