Prenatal diagnosis of cystic adenomatoid malformation of one fetus in a twin pregnancy: An unusual presentation

In 1987 Stork reported a case of a fetal cystic lung anomaly and described it as a mass of cysts lined by proliferating bronchial or cuboidal epithelium and interposed between normal portions of lung. Chin and Tang in 1947 first used the term cystic adenomatoid pulmonary hamartoma in describing a case report, the first in the English language. Since that time a number of cases have been identified postnatally and, since the advent of ultrasonography, prenatally as well. Congenital adenomatoid malformation of the lung (CAML) is a rare but life-threatening condition in the newborn. CAML is a pathologic diagnosis, but clinical signs of the disease, such as maternal polyhydramnios, fetal anasarca, and pulmonary hypoplasia leading to neonatal respiratory distress, can often point toward this diagnosis. We report a case of a twin gestation with CAML type III of one fetus and associated preeclampsia of the mother. To our knowledge no previous report of this association has been published in the literature.