Premenopausal castration and documented coronary atherosclerosis

Joel H. Manchester; Michael V. Herman; Richard Gorlin

doi:10.1016/0002-9149(71)90031-2

Premenopausal castration and documented coronary atherosclerosis

Joel H. Manchester
, Michael V. Herman
, Richard Gorlin

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Twenty surgically castrated women and 65 female control subjects who presented with clinical symptoms of coronary artery disease were studied with selective coronary cinearteriography to determine the prevalence of angiographically documented coronary atherosclerosis. Our results suggest that women who have been surgically castrated for at least 5 years have no more coronary atherosclerosis than their ovary-bearing, age-matched peers, and that surgical castration does not adversely influence the risk of coronary artery disease created by coronary risk factors.

Original language	English
Pages (from-to)	33-37
Number of pages	5
Journal	American Journal of Cardiology
Volume	28
Issue number	1
DOIs	https://doi.org/10.1016/0002-9149(71)90031-2
State	Published - Jul 1971
Externally published	Yes

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@article{4f22666dcec54f068171d875a8168025,

title = "Premenopausal castration and documented coronary atherosclerosis",

abstract = "Twenty surgically castrated women and 65 female control subjects who presented with clinical symptoms of coronary artery disease were studied with selective coronary cinearteriography to determine the prevalence of angiographically documented coronary atherosclerosis. Our results suggest that women who have been surgically castrated for at least 5 years have no more coronary atherosclerosis than their ovary-bearing, age-matched peers, and that surgical castration does not adversely influence the risk of coronary artery disease created by coronary risk factors.",

author = "Manchester, \{Joel H.\} and Herman, \{Michael V.\} and Richard Gorlin",

note = "Funding Information: From the Cardiovascular Division, Department of Medicine, Peter Bent Brigham Hospital and Harvard Medical School, Boston, Mass. This study was supported by U.S. Public Health Service Grant HE 11306, HE 08591 and HE 05679, and a grant from Women{\textquoteright}s Aid for Heart Research, Boston, Mass. Manuscript received July 14, 1970, accepted August 19, 1970.",

year = "1971",

month = jul,

doi = "10.1016/0002-9149(71)90031-2",

language = "English",

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journal = "American Journal of Cardiology",

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T1 - Premenopausal castration and documented coronary atherosclerosis

AU - Manchester, Joel H.

AU - Herman, Michael V.

AU - Gorlin, Richard

N1 - Funding Information: From the Cardiovascular Division, Department of Medicine, Peter Bent Brigham Hospital and Harvard Medical School, Boston, Mass. This study was supported by U.S. Public Health Service Grant HE 11306, HE 08591 and HE 05679, and a grant from Women’s Aid for Heart Research, Boston, Mass. Manuscript received July 14, 1970, accepted August 19, 1970.

PY - 1971/7

Y1 - 1971/7

N2 - Twenty surgically castrated women and 65 female control subjects who presented with clinical symptoms of coronary artery disease were studied with selective coronary cinearteriography to determine the prevalence of angiographically documented coronary atherosclerosis. Our results suggest that women who have been surgically castrated for at least 5 years have no more coronary atherosclerosis than their ovary-bearing, age-matched peers, and that surgical castration does not adversely influence the risk of coronary artery disease created by coronary risk factors.

AB - Twenty surgically castrated women and 65 female control subjects who presented with clinical symptoms of coronary artery disease were studied with selective coronary cinearteriography to determine the prevalence of angiographically documented coronary atherosclerosis. Our results suggest that women who have been surgically castrated for at least 5 years have no more coronary atherosclerosis than their ovary-bearing, age-matched peers, and that surgical castration does not adversely influence the risk of coronary artery disease created by coronary risk factors.

UR - https://www.scopus.com/pages/publications/0015098608

U2 - 10.1016/0002-9149(71)90031-2

DO - 10.1016/0002-9149(71)90031-2

M3 - Article

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SN - 0002-9149

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SP - 33

EP - 37

JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 1

ER -

Premenopausal castration and documented coronary atherosclerosis

Abstract

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