Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression

John O. Brooks, Lara C. Foland-Ross, Paul M. Thompson, Lori L. Altshuler

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A preliminary within-subjects MRI study of seven patients with a diagnosis of bipolar I disorder revealed that, compared to remission, depression was associated with gray matter density increases in subgenual prefrontal cortex, parahippocampal gyrus, and inferior temporal gyri. Decreases were observed in superior and inferior frontal gyri and anterior cingulate.

Original languageEnglish
Pages (from-to)53-55
Number of pages3
JournalPsychiatry Research - Neuroimaging
Volume193
Issue number1
DOIs
StatePublished - 30 Jul 2011
Externally publishedYes

Keywords

  • Bipolar disorder
  • Depression
  • MRI
  • Magnetic resonance imaging
  • Prefrontal

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