Pregnancy in a patient with cystic fibrosis and idiopathic thrombocytopenic purpura

A pregnant patient with cystic fibrosis and idiopathic thrombocytopenic purpura (ITP) is presented. Management of the pregnancy was complicated by the coexistence of the 2 diseases and consisted of antibiotic therapy, prolonged hospitalization, bed rest, exogenous pancreatic enzyme replacement, bronchodilators, blood and platelet transfusions, and high-dose steroids. A good outcome was obtained with cesarean section performed under local anesthesia at 32 weeks' gestation. Recommendations from the literature for the management of each disease are discussed.