TY - JOUR
T1 - Predictors of psychosocial impairment in a transdiagnostic sample
T2 - Unique effects of repetitive negative thinking
AU - Adamis, Alexandra M.
AU - Lebovitz, Julia G.
AU - Oberlin, Lauren
AU - Chen, Serena
AU - Phan, Dustin
AU - Burns, Katharine C.
AU - Gunning, Faith M.
AU - Burdick, Katherine E.
N1 - Publisher Copyright:
© 2024 Elsevier B.V.
PY - 2024/12
Y1 - 2024/12
N2 - Background: Repetitive negative thinking (RNT) is a transdiagnostic process involving perseverative, unproductive, and uncontrollable thoughts. Although RNT may impede adaptive psychosocial functioning by prolonging negative mood states, strengthening cognitive biases, and preventing effective problem-solving, the extent to which RNT is associated with risk for poor psychosocial outcomes is unclear. Given that this has clear transdiagnostic treatment implications, the present study aimed to isolate the unique relationship of RNT with social functioning and life satisfaction in a mixed clinical and non-clinical sample. Methods: In 201 mid-to-later life adult participants (27 with primary diagnoses of bipolar disorder, 84 with major depressive disorder, and 90 healthy volunteers), we measured RNT, social functioning, life satisfaction, trait rumination, DSM-5 diagnoses, depressive symptoms, manic symptoms, cognitive control performance, and global cognitive functioning. Results: Linear regression models revealed that RNT, but not rumination, was significantly associated with poorer social functioning (β = 0.42 p <.001) and reduced life satisfaction (β = −0.42, p <.001) after controlling for clinical and cognitive covariates. Limitations: Limited demographic diversity, cross-sectional design, self-reporting of outcomes. Conclusions: Results suggest that RNT may confer risk for key psychosocial outcomes during middle to later adulthood, over and above the effects of clinical and cognitive variables and independent of diagnostic status. Findings lend support to the notion of RNT as a transdiagnostic process and suggest that RNT may be an important therapeutic target for adults with poor social functioning and/or reduced life satisfaction.
AB - Background: Repetitive negative thinking (RNT) is a transdiagnostic process involving perseverative, unproductive, and uncontrollable thoughts. Although RNT may impede adaptive psychosocial functioning by prolonging negative mood states, strengthening cognitive biases, and preventing effective problem-solving, the extent to which RNT is associated with risk for poor psychosocial outcomes is unclear. Given that this has clear transdiagnostic treatment implications, the present study aimed to isolate the unique relationship of RNT with social functioning and life satisfaction in a mixed clinical and non-clinical sample. Methods: In 201 mid-to-later life adult participants (27 with primary diagnoses of bipolar disorder, 84 with major depressive disorder, and 90 healthy volunteers), we measured RNT, social functioning, life satisfaction, trait rumination, DSM-5 diagnoses, depressive symptoms, manic symptoms, cognitive control performance, and global cognitive functioning. Results: Linear regression models revealed that RNT, but not rumination, was significantly associated with poorer social functioning (β = 0.42 p <.001) and reduced life satisfaction (β = −0.42, p <.001) after controlling for clinical and cognitive covariates. Limitations: Limited demographic diversity, cross-sectional design, self-reporting of outcomes. Conclusions: Results suggest that RNT may confer risk for key psychosocial outcomes during middle to later adulthood, over and above the effects of clinical and cognitive variables and independent of diagnostic status. Findings lend support to the notion of RNT as a transdiagnostic process and suggest that RNT may be an important therapeutic target for adults with poor social functioning and/or reduced life satisfaction.
KW - Bipolar disorder
KW - Cognition
KW - Disability
KW - Major depressive disorder
KW - Repetitive negative thinking
KW - Rumination
UR - http://www.scopus.com/inward/record.url?scp=85202567264&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2024.08.054
DO - 10.1016/j.jad.2024.08.054
M3 - Article
C2 - 39142590
AN - SCOPUS:85202567264
SN - 0165-0327
VL - 366
SP - 74
EP - 82
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -