Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana

Sweta M. Patel; Lisa Spees; Marek Smieja; Kathy Luinstra; Andrew P. Steenhoff; Kristen A. Feemster; Tonya Arscott-Mills; Sefelani Boiditswe; Mohamed Z. Patel; Samir S. Shah; Coleen K. Cunningham; Matthew S. Kelly

doi:10.1097/INF.0000000000002168

Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana

Sweta M. Patel
, Lisa Spees
, Marek Smieja
, Kathy Luinstra
, Andrew P. Steenhoff
, Kristen A. Feemster
, Tonya Arscott-Mills
, Sefelani Boiditswe
, Mohamed Z. Patel
, Samir S. Shah
, Coleen K. Cunningham
, Matthew S. Kelly

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.

Original language	English
Pages (from-to)	525-527
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	38
Issue number	5
DOIs	https://doi.org/10.1097/INF.0000000000002168
State	Published - 1 May 2019
Externally published	Yes

Keywords

Botswana
HIV-exposed
children
outcomes
respiratory syncytial virus

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10.1097/INF.0000000000002168

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Patel, S. M., Spees, L., Smieja, M., Luinstra, K., Steenhoff, A. P., Feemster, K. A., Arscott-Mills, T., Boiditswe, S., Patel, M. Z., Shah, S. S., Cunningham, C. K., & Kelly, M. S. (2019). Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana. Pediatric Infectious Disease Journal, 38(5), 525-527. https://doi.org/10.1097/INF.0000000000002168

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title = "Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana",

abstract = "Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90\% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.",

keywords = "Botswana, HIV-exposed, children, outcomes, respiratory syncytial virus",

author = "Patel, \{Sweta M.\} and Lisa Spees and Marek Smieja and Kathy Luinstra and Steenhoff, \{Andrew P.\} and Feemster, \{Kristen A.\} and Tonya Arscott-Mills and Sefelani Boiditswe and Patel, \{Mohamed Z.\} and Shah, \{Samir S.\} and Cunningham, \{Coleen K.\} and Kelly, \{Matthew S.\}",

year = "2019",

month = may,

day = "1",

doi = "10.1097/INF.0000000000002168",

language = "English",

volume = "38",

pages = "525--527",

journal = "Pediatric Infectious Disease Journal",

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}

Patel, SM, Spees, L, Smieja, M, Luinstra, K, Steenhoff, AP, Feemster, KA, Arscott-Mills, T, Boiditswe, S, Patel, MZ, Shah, SS, Cunningham, CK & Kelly, MS 2019, 'Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana', Pediatric Infectious Disease Journal, vol. 38, no. 5, pp. 525-527. https://doi.org/10.1097/INF.0000000000002168

TY - JOUR

T1 - Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana

AU - Patel, Sweta M.

AU - Spees, Lisa

AU - Smieja, Marek

AU - Luinstra, Kathy

AU - Steenhoff, Andrew P.

AU - Feemster, Kristen A.

AU - Arscott-Mills, Tonya

AU - Boiditswe, Sefelani

AU - Patel, Mohamed Z.

AU - Shah, Samir S.

AU - Cunningham, Coleen K.

AU - Kelly, Matthew S.

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.

AB - Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.

KW - Botswana

KW - HIV-exposed

KW - children

KW - outcomes

KW - respiratory syncytial virus

UR - https://www.scopus.com/pages/publications/85064886190

U2 - 10.1097/INF.0000000000002168

DO - 10.1097/INF.0000000000002168

M3 - Article

C2 - 30543564

AN - SCOPUS:85064886190

SN - 0891-3668

VL - 38

SP - 525

EP - 527

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 5

ER -

Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana

Abstract

Keywords

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