Predictors of Poor Outcomes among Infants with Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana

Sweta M. Patel, Lisa Spees, Marek Smieja, Kathy Luinstra, Andrew P. Steenhoff, Kristen A. Feemster, Tonya Arscott-Mills, Sefelani Boiditswe, Mohamed Z. Patel, Samir S. Shah, Coleen K. Cunningham, Matthew S. Kelly

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.

Original languageEnglish
Pages (from-to)525-527
Number of pages3
JournalPediatric Infectious Disease Journal
Volume38
Issue number5
DOIs
StatePublished - 1 May 2019
Externally publishedYes

Keywords

  • Botswana
  • HIV-exposed
  • children
  • outcomes
  • respiratory syncytial virus

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