Abstract
Endocrine tumors are ubiquitous and can arise in many organs such as the pituitary, the pancreas, the ovaries, the testicles, the thyroid, the parathyroid, and the adrenal glands. Many of these tumors retain the ability to secrete hormones which can be the source of their symptomatology. In this chapter, we will mainly cover biomarkers associated with thyroid cancer - the most common malignancy of the endocrine system- and briefly touch upon other tumors such as the parathyroid carcinoma and adrenal gland neoplasia.
| Original language | English |
|---|---|
| Title of host publication | Predictive Biomarkers in Oncology |
| Subtitle of host publication | Applications in Precision Medicine |
| Publisher | Springer International Publishing |
| Pages | 493-500 |
| Number of pages | 8 |
| ISBN (Electronic) | 9783319952284 |
| ISBN (Print) | 9783319952277 |
| DOIs | |
| State | Published - 1 Jan 2018 |
| Externally published | Yes |
Keywords
- Adrenocortical carcinoma
- Follicular thyroid carcinoma
- Mitogen-activated protein kinase (MAPK) signaling pathway
- PI3K/Akt/mTOR signaling pathway
- Papillary thyroid carcinoma
- Paraganglioma
- Parathyroid carcinoma
- Pheochromocytoma
- Tyrosine kinase inhibitors