Prediction of Primary Admission Total Charges Following Single-Level Lumbar Arthrodesis Utilizing Machine Learning

Study Design: Retrospective analysis utilizing machine learning. Objectives: This study aims to identify the key factors influencing total charges during the primary admission period following single-level lumbar arthrodesis, using machine learning models to enhance predictive accuracy. Methods: Data were extracted from the National Inpatient Sample (NIS) database and analyzed using various machine learning models, including random forest, gradient boosting trees, and logistic regression. A total of 78,022 unweighted cases of patients who underwent single-level lumbar arthrodesis were identified using the NIS database from 2016 to 2020. Variables included hospital size, region, patient-specific factors, and procedural details. Multivariate linear regression was also used to identify charge-related variables. Results: The average total charge for single-level lumbar arthrodesis was $145,600 ± $102,500. Significant predictors of charge included length of stay, hospital size, hospital ownership, and region. Private investor-owned hospitals and procedures performed in the Western U.S. were associated with higher charges. Random forest models demonstrated superior predictive accuracy with an AUC of .866, outperforming other models. Conclusions: Hospital characteristics, regional factors, and patient-specific variables significantly influence the charges of single-level lumbar arthrodesis. Machine learning models, particularly random forest, provide robust tools for predicting healthcare costs, enabling better resource allocation and decision-making. Future research should explore these dynamics further to optimize cost management and improve care quality.