TY - JOUR
T1 - Prediction of clinical outcomes in patients with unprotected left main trifurcation lesions treated by drug-eluting stents
T2 - Importance of 2-stent technique and SYNTAX score
AU - Chen, Shao Liang
AU - Ye, Fey
AU - Zhang, Jun Jie
AU - Hu, Zuo Ying
AU - Tian, Nai Liang
AU - Zhang, Jun Xia
AU - Kwan, Tak W.
PY - 2010/8
Y1 - 2010/8
N2 - Background: There were insufficient data on the prognosis of stenting for patients with trifurcated unprotected left main lesions (UPLMS). Methods: From the SPEED (stents for percutaneous treatment of coronary artery disease) registry of all percutaneous coronary interventions (PCI) for all types of UPLMS, data of 44 patients with trifurcated UPLMS were selected and analyzed. Results: Patients were divided into one-stent (N = 23) or 2-stent (N = 21) groups. Clinical follow-up was available for 100%, and angiographic follow-up at 8 month was available for 91.3%. There were no differences in myocardial infarction, cardiac death, and stent thrombosis between groups. However, the target lesion revascularization (TLR) and target vessel revascularization (TVR) in the 1-stent group was lower when compared to the 2-stent group (13.0% vs. 23.8%, P = 0.004; 13.0% vs. 28.6%, P = 0.003, respectively). Cumulative survival free from major adverse cardiovascular events (MACE) in the 1-stent group was higher than the 2-stent group (65.2% vs. 57.1%, P = 0.033). Analysis of the receiver operator curve (ROC) of the Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score showed the area under the curve was 0.414 (standard error = 0.089, 95% CI 0.240-0.589, P = 0.348). Conclusions: In patients with trifurcated UPLMS, higher TLRTVR and lower cumulative survival from MACE were seen in the 2-stent group when compared to the 1-stent group. The SYNTAX scoring system had no predictive value of outcomes for patients with stenting of trifurcated UPLMS.
AB - Background: There were insufficient data on the prognosis of stenting for patients with trifurcated unprotected left main lesions (UPLMS). Methods: From the SPEED (stents for percutaneous treatment of coronary artery disease) registry of all percutaneous coronary interventions (PCI) for all types of UPLMS, data of 44 patients with trifurcated UPLMS were selected and analyzed. Results: Patients were divided into one-stent (N = 23) or 2-stent (N = 21) groups. Clinical follow-up was available for 100%, and angiographic follow-up at 8 month was available for 91.3%. There were no differences in myocardial infarction, cardiac death, and stent thrombosis between groups. However, the target lesion revascularization (TLR) and target vessel revascularization (TVR) in the 1-stent group was lower when compared to the 2-stent group (13.0% vs. 23.8%, P = 0.004; 13.0% vs. 28.6%, P = 0.003, respectively). Cumulative survival free from major adverse cardiovascular events (MACE) in the 1-stent group was higher than the 2-stent group (65.2% vs. 57.1%, P = 0.033). Analysis of the receiver operator curve (ROC) of the Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score showed the area under the curve was 0.414 (standard error = 0.089, 95% CI 0.240-0.589, P = 0.348). Conclusions: In patients with trifurcated UPLMS, higher TLRTVR and lower cumulative survival from MACE were seen in the 2-stent group when compared to the 1-stent group. The SYNTAX scoring system had no predictive value of outcomes for patients with stenting of trifurcated UPLMS.
UR - http://www.scopus.com/inward/record.url?scp=77955867210&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8183.2010.00569.x
DO - 10.1111/j.1540-8183.2010.00569.x
M3 - Article
C2 - 20642480
AN - SCOPUS:77955867210
SN - 0896-4327
VL - 23
SP - 352
EP - 357
JO - Journal of Interventional Cardiology
JF - Journal of Interventional Cardiology
IS - 4
ER -