Practicing antimicrobial stewardship: De-escalating antibiotics in patients with acute myeloid leukemia and neutropenic fever

Risa Fuller, Erin Moshier, Samantha E. Jacobs, Douglas Tremblay, Guido Lancman, Alexander Coltoff, Jessica Caro, John Mascarenhas, Meenakshi Rana

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.

Original languageEnglish
Article numberofaa138
JournalOpen Forum Infectious Diseases
Volume7
Issue number5
DOIs
StatePublished - 2020

Keywords

  • Acute myeloid leukemia
  • Antimicrobial stewardship
  • Neutropenic fever

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