Practicing antimicrobial stewardship: De-escalating antibiotics in patients with acute myeloid leukemia and neutropenic fever

Risa Fuller; Erin Moshier; Samantha E. Jacobs; Douglas Tremblay; Guido Lancman; Alexander Coltoff; Jessica Caro; John Mascarenhas; Meenakshi Rana

doi:10.1093/OFID/OFAA138

Practicing antimicrobial stewardship: De-escalating antibiotics in patients with acute myeloid leukemia and neutropenic fever

Risa Fuller, Erin Moshier, Samantha E. Jacobs, Douglas Tremblay, Guido Lancman, Alexander Coltoff, Jessica Caro, John Mascarenhas, Meenakshi Rana

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.

Original language	English
Article number	ofaa138
Journal	Open Forum Infectious Diseases
Volume	7
Issue number	5
DOIs	https://doi.org/10.1093/OFID/OFAA138
State	Published - 2020

Keywords

Acute myeloid leukemia
Antimicrobial stewardship
Neutropenic fever

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10.1093/OFID/OFAA138

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abstract = "We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.",

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AU - Tremblay, Douglas

AU - Lancman, Guido

AU - Coltoff, Alexander

AU - Caro, Jessica

AU - Mascarenhas, John

AU - Rana, Meenakshi

PY - 2020

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AB - We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.

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KW - Neutropenic fever

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Practicing antimicrobial stewardship: De-escalating antibiotics in patients with acute myeloid leukemia and neutropenic fever

Abstract

Keywords

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