TY - JOUR
T1 - Practice patterns of US neurologists in patients with CIS, RRMS, or RIS
T2 - A consensus study
AU - Tornatore, Carlo
AU - Theodore Phillips, J.
AU - Khan, Omar
AU - Miller, Aaron E.
AU - Barnes, Christopher J.
PY - 2012/3
Y1 - 2012/3
N2 - We assess current practice patterns of US neurologists in patients with clinically isolated syndrome (CIS), relapsing-remitting multiple sclerosis (RRMS), and radiologically isolated syndrome (RIS) using case-based surveys. For CIS, 87% recommended initiation of disease-modifying therapy (DMT) with MRI brain lesions. An injectable DMT was recommended by 90%-98% for treatment-naive, mild RRMS patients. There was 97% consensus to treat highly active RRMS, but no consensus on therapy choice. With RIS, there was consensus not to initiate treatment with brain but no spinal MRI lesions. Current US treatment patterns emphasize MRI in MS diagnosis and subsequent treatment decisions, treatment of early disease, aggressive initial treatment of highly active MS, and close patient monitoring.
AB - We assess current practice patterns of US neurologists in patients with clinically isolated syndrome (CIS), relapsing-remitting multiple sclerosis (RRMS), and radiologically isolated syndrome (RIS) using case-based surveys. For CIS, 87% recommended initiation of disease-modifying therapy (DMT) with MRI brain lesions. An injectable DMT was recommended by 90%-98% for treatment-naive, mild RRMS patients. There was 97% consensus to treat highly active RRMS, but no consensus on therapy choice. With RIS, there was consensus not to initiate treatment with brain but no spinal MRI lesions. Current US treatment patterns emphasize MRI in MS diagnosis and subsequent treatment decisions, treatment of early disease, aggressive initial treatment of highly active MS, and close patient monitoring.
UR - http://www.scopus.com/inward/record.url?scp=84875823480&partnerID=8YFLogxK
U2 - 10.1212/CPJ.0b013e31824cb09b
DO - 10.1212/CPJ.0b013e31824cb09b
M3 - Article
AN - SCOPUS:84875823480
SN - 2163-0402
VL - 2
SP - 48
EP - 57
JO - Neurology: Clinical Practice
JF - Neurology: Clinical Practice
IS - 1
ER -