Abstract
Recent advances in the treatment of alcoholic hepatitis (AH) have reinforced the utility of glucocorticoids, a treatment that has been in use for nearly 4 decades, to enhance short-term survival. As multi-institutional consortia research new therapeutic advances, this orphan disease, which afflicts younger patients and has poor outcomes, continues to be difficult to manage. AH has a protean clinical presentation and course, with various prediction models and treatment approaches that can challenge even experienced providers. This review addresses 4 key controversies and other practical issues associated with the diagnosis, prognosis, management, and treatment of patients with AH.
| Original language | English |
|---|---|
| Pages (from-to) | 478-489 |
| Number of pages | 12 |
| Journal | Gastroenterology and Hepatology |
| Volume | 12 |
| Issue number | 8 |
| State | Published - Aug 2016 |
Keywords
- Alcoholic hepatitis
- Discriminant function
- Early liver transplantation
- Glasgow alcoholic hepatitis score
- Lille model
- Model for end-stage liver disease