Potentiality of bacterial cellulose as the scaffold of tissue engineering of cornea

Hui Jia, Yuanyuan Jia, Jiao Wang, Yuan Hu, Yuan Zhang, Shiru Jia

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

27 Scopus citations

Abstract

The bacterial cellulose (BC) secreted by Gluconacetobacter xylinus was explored as a novel scaffold material due to its unusual biocompatibility, light transmittance and material properties. The specific surface area of the frozen-dried BC sheet based on BET isotherm was 22.886 m2/g, and the porosity was around 90%. It is known by SEM graphs that significant difference in porosity and pore size exists in the two sides of air-dried BC sheets. The width of cellulose ribbons was 10 nm to 100 nm known by AFM image. The examination of the growth of human corneal stromal cells on BC demonstrated that the material supported the growth and proliferation of human corneal stromal cells. The ingrowth of corneal stromal cells into the scaffold was verified by Laser Scanning Confocal Microscope. The results suggest the potentiality for this biomaterial as a scaffold for tissue engineering of artificial cornea.

Original languageEnglish
Title of host publicationProceedings of the 2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009
DOIs
StatePublished - 2009
Externally publishedYes
Event2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009 - Tianjin, China
Duration: 17 Oct 200919 Oct 2009

Publication series

NameProceedings of the 2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009

Conference

Conference2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009
Country/TerritoryChina
CityTianjin
Period17/10/0919/10/09

Keywords

  • Bacterial cellulose
  • Cornea
  • Corneal stromal cells
  • Scaffold
  • Tissue engineering

Fingerprint

Dive into the research topics of 'Potentiality of bacterial cellulose as the scaffold of tissue engineering of cornea'. Together they form a unique fingerprint.

Cite this