Reverse genetics techniques have been established for the introduction of specific mutations into the influenza A virus genes. These techniques allowed the generation of influenza virus vectors expressing foreign antigens. Expression of tumor-associated antigens (TAAs) by influenza virus vectors might represent a promising way to induce potent cellular immune responses against cancer cells, leading to tumor regression.

Original languageEnglish
Pages (from-to)1029-1035
Number of pages7
JournalInternational Congress Series
Issue numberC
StatePublished - 1 Oct 2001


  • Cancer therapy
  • Influenza virus
  • Reverse genetics
  • Tumor-associated antigens


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