Potential adverse effects of norepinephrine on cortical somatosensory-evoked potentials during carotid endarterectomy: A case report

Philip David Bamberger; Sedat Ulkatan; Estela Lladó Carbó; Vedran Deletis; Alan I. Benvenisty

doi:10.1016/j.jclinane.2010.12.029

Potential adverse effects of norepinephrine on cortical somatosensory-evoked potentials during carotid endarterectomy: A case report

Philip David Bamberger, Sedat Ulkatan, Estela Lladó Carbó, Vedran Deletis, Alan I. Benvenisty

Research output: Contribution to journal › Article › peer-review

Abstract

The cerebral metabolic and vascular effects of intravenous norepinephrine have been shown in an animal model using somatosensory-evoked potentials (SSEPs). A case of intravenous norepinephrine resulting in a decrease in SSEP amplitude (of greater than 50%) despite no significant change in blood pressure, prior to cross-clamping during a carotid endarterectomy is presented. This finding may have implications for the use of norepinephrine in the critical care unit as well as the operating room.

Original language	English
Pages (from-to)	657-660
Number of pages	4
Journal	Journal of Clinical Anesthesia
Volume	23
Issue number	8
DOIs	https://doi.org/10.1016/j.jclinane.2010.12.029
State	Published - Dec 2011
Externally published	Yes

Keywords

Carotid endarterectomy
Neurophysiologic monitoring
Norepinephrine
Somatosensory-evoked potentials

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10.1016/j.jclinane.2010.12.029

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title = "Potential adverse effects of norepinephrine on cortical somatosensory-evoked potentials during carotid endarterectomy: A case report",

abstract = "The cerebral metabolic and vascular effects of intravenous norepinephrine have been shown in an animal model using somatosensory-evoked potentials (SSEPs). A case of intravenous norepinephrine resulting in a decrease in SSEP amplitude (of greater than 50%) despite no significant change in blood pressure, prior to cross-clamping during a carotid endarterectomy is presented. This finding may have implications for the use of norepinephrine in the critical care unit as well as the operating room.",

keywords = "Carotid endarterectomy, Neurophysiologic monitoring, Norepinephrine, Somatosensory-evoked potentials",

author = "Bamberger, {Philip David} and Sedat Ulkatan and Carb{\'o}, {Estela Llad{\'o}} and Vedran Deletis and Benvenisty, {Alan I.}",

year = "2011",

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T2 - A case report

AU - Bamberger, Philip David

AU - Ulkatan, Sedat

AU - Carbó, Estela Lladó

AU - Deletis, Vedran

AU - Benvenisty, Alan I.

PY - 2011/12

Y1 - 2011/12

N2 - The cerebral metabolic and vascular effects of intravenous norepinephrine have been shown in an animal model using somatosensory-evoked potentials (SSEPs). A case of intravenous norepinephrine resulting in a decrease in SSEP amplitude (of greater than 50%) despite no significant change in blood pressure, prior to cross-clamping during a carotid endarterectomy is presented. This finding may have implications for the use of norepinephrine in the critical care unit as well as the operating room.

AB - The cerebral metabolic and vascular effects of intravenous norepinephrine have been shown in an animal model using somatosensory-evoked potentials (SSEPs). A case of intravenous norepinephrine resulting in a decrease in SSEP amplitude (of greater than 50%) despite no significant change in blood pressure, prior to cross-clamping during a carotid endarterectomy is presented. This finding may have implications for the use of norepinephrine in the critical care unit as well as the operating room.

KW - Carotid endarterectomy

KW - Neurophysiologic monitoring

KW - Norepinephrine

KW - Somatosensory-evoked potentials

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JO - Journal of Clinical Anesthesia

JF - Journal of Clinical Anesthesia

IS - 8

ER -

Potential adverse effects of norepinephrine on cortical somatosensory-evoked potentials during carotid endarterectomy: A case report

Abstract

Keywords

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