Abstract
Cell-based medicine has seen transformative change over the past decades with bone marrow, umbilical cord, solid organ, and fecal transplantation combined with traditional multiagent chemotherapy, immunotherapy, and maintenance regimens with excellent response and/or subsequent sequelae, a range of pathology, and molecular monitoring. The range of pathology includes reactive hyperplasia, polymorphous to monomorphic proliferations with polyclonal, oligoclonal, and clonal changes that can be tracked by a range of techniques for minimal residual disease.
Original language | English |
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Title of host publication | Atlas of Diagnostic Hematology |
Publisher | Elsevier |
Pages | 322-338 |
Number of pages | 17 |
ISBN (Electronic) | 9780323567381 |
ISBN (Print) | 9780323567343 |
DOIs | |
State | Published - 1 Jan 2020 |
Keywords
- bone marrow transplantation
- cell-based medicine
- cytogenomics
- fluorescence in situ hybridization (FISH)
- graft-versus-host disease
- karyotype
- molecular
- molecular genetics
- pathology
- posttransplant lymphoproliferative disorders (PTLD)
- transplantation