Posttransplant Lymphoproliferative Disorders and Immunodeficiency

Alla Keyzner, Douglas Tremblay, Julie Teruya-Feldstein

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Cell-based medicine has seen transformative change over the past decades with bone marrow, umbilical cord, solid organ, and fecal transplantation combined with traditional multiagent chemotherapy, immunotherapy, and maintenance regimens with excellent response and/or subsequent sequelae, a range of pathology, and molecular monitoring. The range of pathology includes reactive hyperplasia, polymorphous to monomorphic proliferations with polyclonal, oligoclonal, and clonal changes that can be tracked by a range of techniques for minimal residual disease.

Original languageEnglish
Title of host publicationAtlas of Diagnostic Hematology
Number of pages17
ISBN (Electronic)9780323567381
ISBN (Print)9780323567343
StatePublished - 1 Jan 2020


  • bone marrow transplantation
  • cell-based medicine
  • cytogenomics
  • fluorescence in situ hybridization (FISH)
  • graft-versus-host disease
  • karyotype
  • molecular
  • molecular genetics
  • pathology
  • posttransplant lymphoproliferative disorders (PTLD)
  • transplantation


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