Abstract
This chapter discusses the role of caffeine, Gabapentin, and Epidural blood patch in postdural puncture headache. Postdural puncture headache (PDPH) complicates up to 5% of spinal taps and is also frequently seen postpartum (from anesthesia-related dural puncture). The best treatment for PDPH is prevention. Although a variety of approaches to PDPH have been mentioned in reviews, the drug therapy with the most supporting evidence is caffeine. Oral formulations of caffeine (300 mg per dose) are more effective than placebo for PDPH. Thrice-daily gabapentin is reported in case series to have efficacy in PDPH. The evidence is preliminary, but administration of this anticonvulsant is of potential utility when caffeine fails or is not an option, and patients are not candidates for (or refuse) epidural blood patch. The responsibility of the acute care provider to the patient with PDPH is often administration of temporizing pharmacotherapy pending availability of an epidural blood patch.
Original language | English |
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Title of host publication | Emergency Department Analgesia |
Subtitle of host publication | An Evidence-Based Guide |
Publisher | Cambridge University Press |
Pages | 351-353 |
Number of pages | 3 |
ISBN (Electronic) | 9780511544835 |
ISBN (Print) | 9780521696012 |
DOIs | |
State | Published - 1 Jan 2008 |