11 Scopus citations


Background. Post-transplant lymphoproliferative disorder involving the female genital tract is a rare event. Case. A 67-year-old female status post orthotopic liver transplant 5 years previously for hepatitis B and sarcoidosis presented with vaginal bleeding. Endometrial biopsy revealed a high-grade malignant tumor with immunologic marker studies consistent with lymphoma. The patient underwent an exploratory laparotomy, modified radical hysterectomy, bilateral salpingo oophorectomy, bilateral selective pelvic and para-aortic lymphadenectomy, and omentectomy. Final pathology confirmed monomorphic B-cell post-transplantation lymphoproliferative disorder consistent with non-Hodgkin's B cell lymphoma confined to the endocervix and lower uterine segment. She remains recurrence free after 4 years with no adjuvant therapy. Conclusion. Post-transplant complications can present in the female reproductive organs. Gynecologic oncologists need to be aware of this disease process when treating patients for gynecologic symptoms after transplant surgery.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalGynecologic Oncology
Issue number1
StatePublished - Apr 2005


  • Cervix
  • Epstein-Barr virus
  • Post-transplant lymphoproliferative disorder


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