Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States

Sesh A. Sundararaman; Karen L. Hanze Villavicencio; Brianne Roper; Ziyi Wang; Amy K.F. Davis; Jonathan A. Mayhew; Michelle L. Wang; Nina L. Tang; Vijaya L. Soma; Gail F. Shust; Margaret E. Feeney; Indi Trehan; Jill E. Weatherhead; Chandy C. John; Jeffrey S. Gerber; Audrey R. Odom John

doi:10.1093/jpids/piae080

Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States

Sesh A. Sundararaman
, Karen L. Hanze Villavicencio
, Brianne Roper
, Ziyi Wang
, Amy K.F. Davis
, Jonathan A. Mayhew
, Michelle L. Wang
, Nina L. Tang
, Vijaya L. Soma
, Gail F. Shust
, Margaret E. Feeney
, Indi Trehan
, Jill E. Weatherhead
, Chandy C. John
, Jeffrey S. Gerber
, Audrey R. Odom John

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

Original language	English
Pages (from-to)	533-536
Number of pages	4
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	13
Issue number	10
DOIs	https://doi.org/10.1093/jpids/piae080
State	Published - 1 Oct 2024
Externally published	Yes

Keywords

adverse drug reaction
artesunate
hemolytic anemia
malaria
pediatric
post-artesunate delayed hemolysis

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10.1093/jpids/piae080

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Sundararaman, S. A., Hanze Villavicencio, K. L., Roper, B., Wang, Z., Davis, A. K. F., Mayhew, J. A., Wang, M. L., Tang, N. L., Soma, V. L., Shust, G. F., Feeney, M. E., Trehan, I., Weatherhead, J. E., John, C. C., Gerber, J. S., & Odom John, A. R. (2024). Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States. Journal of the Pediatric Infectious Diseases Society, 13(10), 533-536. https://doi.org/10.1093/jpids/piae080

@article{a04a4c6f1c374a94a690fe5722efe77a,

title = "Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States",

abstract = "Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.",

keywords = "adverse drug reaction, artesunate, hemolytic anemia, malaria, pediatric, post-artesunate delayed hemolysis",

author = "Sundararaman, \{Sesh A.\} and \{Hanze Villavicencio\}, \{Karen L.\} and Brianne Roper and Ziyi Wang and Davis, \{Amy K.F.\} and Mayhew, \{Jonathan A.\} and Wang, \{Michelle L.\} and Tang, \{Nina L.\} and Soma, \{Vijaya L.\} and Shust, \{Gail F.\} and Feeney, \{Margaret E.\} and Indi Trehan and Weatherhead, \{Jill E.\} and John, \{Chandy C.\} and Gerber, \{Jeffrey S.\} and \{Odom John\}, \{Audrey R.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = oct,

day = "1",

doi = "10.1093/jpids/piae080",

language = "English",

volume = "13",

pages = "533--536",

journal = "Journal of the Pediatric Infectious Diseases Society",

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publisher = "Oxford University Press",

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}

Sundararaman, SA, Hanze Villavicencio, KL, Roper, B, Wang, Z, Davis, AKF, Mayhew, JA, Wang, ML, Tang, NL, Soma, VL, Shust, GF, Feeney, ME, Trehan, I, Weatherhead, JE, John, CC, Gerber, JS & Odom John, AR 2024, 'Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States', Journal of the Pediatric Infectious Diseases Society, vol. 13, no. 10, pp. 533-536. https://doi.org/10.1093/jpids/piae080

TY - JOUR

T1 - Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States

AU - Sundararaman, Sesh A.

AU - Hanze Villavicencio, Karen L.

AU - Roper, Brianne

AU - Wang, Ziyi

AU - Davis, Amy K.F.

AU - Mayhew, Jonathan A.

AU - Wang, Michelle L.

AU - Tang, Nina L.

AU - Soma, Vijaya L.

AU - Shust, Gail F.

AU - Feeney, Margaret E.

AU - Trehan, Indi

AU - Weatherhead, Jill E.

AU - John, Chandy C.

AU - Gerber, Jeffrey S.

AU - Odom John, Audrey R.

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/10/1

Y1 - 2024/10/1

N2 - Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

AB - Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

KW - adverse drug reaction

KW - artesunate

KW - hemolytic anemia

KW - malaria

KW - pediatric

KW - post-artesunate delayed hemolysis

UR - https://www.scopus.com/pages/publications/85208602062

U2 - 10.1093/jpids/piae080

DO - 10.1093/jpids/piae080

M3 - Article

C2 - 39149792

AN - SCOPUS:85208602062

SN - 2048-7193

VL - 13

SP - 533

EP - 536

JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

IS - 10

ER -

Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States

Abstract

Keywords

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