Abstract
The authors investigated the potential association of human primary CNS non-Hodgkin lymphoma (PCNSL) with polyomavirus in HIV-1 infected and uninfected individuals. Immunohistochemical analysis of CNS biopsies from 19 HIV-negative and 17 HIV-positive patients and PCR analysis of 12 HIV-negative and 14 HIV-positive patients revealed that the lymphomas were uniformly negative for polyomaviruses. The authors conclude that polyomaviruses are unlikely to be related to the pathogenesis of most PCNSL.
| Original language | English |
|---|---|
| Pages (from-to) | 1299-1301 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 63 |
| Issue number | 7 |
| DOIs | |
| State | Published - 12 Oct 2004 |