Polyomaviruses and primary central nervous system lymphomas

Jacinta M. Murray, Susan Morgello

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The authors investigated the potential association of human primary CNS non-Hodgkin lymphoma (PCNSL) with polyomavirus in HIV-1 infected and uninfected individuals. Immunohistochemical analysis of CNS biopsies from 19 HIV-negative and 17 HIV-positive patients and PCR analysis of 12 HIV-negative and 14 HIV-positive patients revealed that the lymphomas were uniformly negative for polyomaviruses. The authors conclude that polyomaviruses are unlikely to be related to the pathogenesis of most PCNSL.

Original languageEnglish
Pages (from-to)1299-1301
Number of pages3
JournalNeurology
Volume63
Issue number7
DOIs
StatePublished - 12 Oct 2004

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