Polymorphisms in the human SNAIL (SNAI1) gene

K. Okajima; W. A. Paznekas; T. Burstyn; E. W. Jabs

doi:10.1006/mcpr.2000.0332

Polymorphisms in the human SNAIL (SNAI1) gene

K. Okajima
, W. A. Paznekas
, T. Burstyn
, E. W. Jabs

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5′UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.

Original language	English
Pages (from-to)	53-55
Number of pages	3
Journal	Molecular and Cellular Probes
Volume	15
Issue number	1
DOIs	https://doi.org/10.1006/mcpr.2000.0332
State	Published - 2001
Externally published	Yes

Keywords

Single nucleotide polymorphism (SNP)
Snail
Zinc finger protein

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10.1006/mcpr.2000.0332

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title = "Polymorphisms in the human SNAIL (SNAI1) gene",

abstract = "The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5′UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.",

keywords = "Single nucleotide polymorphism (SNP), Snail, Zinc finger protein",

author = "K. Okajima and Paznekas, \{W. A.\} and T. Burstyn and Jabs, \{E. W.\}",

note = "Funding Information: This work was supported by NIH grant P60 DE13078.",

year = "2001",

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T1 - Polymorphisms in the human SNAIL (SNAI1) gene

AU - Okajima, K.

AU - Paznekas, W. A.

AU - Burstyn, T.

AU - Jabs, E. W.

N1 - Funding Information: This work was supported by NIH grant P60 DE13078.

PY - 2001

Y1 - 2001

N2 - The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5′UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.

AB - The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5′UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.

KW - Single nucleotide polymorphism (SNP)

KW - Snail

KW - Zinc finger protein

UR - https://www.scopus.com/pages/publications/0035129242

U2 - 10.1006/mcpr.2000.0332

DO - 10.1006/mcpr.2000.0332

M3 - Article

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AN - SCOPUS:0035129242

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SP - 53

EP - 55

JO - Molecular and Cellular Probes

JF - Molecular and Cellular Probes

IS - 1

ER -

Polymorphisms in the human SNAIL (SNAI1) gene

Abstract

Keywords

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