TY - JOUR
T1 - Polycystic Ovary Syndrome
T2 - A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
AU - Futterweit, Walter
PY - 2007/12
Y1 - 2007/12
N2 - Patients who have polycystic ovary syndrome (PCOS) present with infertility, recurrent miscarriages, menstrual irregularities, hirsutism, and acne. Many also have metabolic and hormonal abnormalities that can significantly increase risk for coronary artery disease, type 2 diabetes mellitus, and endometrial carcinoma. PCOS patients should be screened for obstructive sleep apnea. Early recognition may reverse physical signs of the disease, while correcting the metabolic abnormalities that can pose significant health risk if untreated. Although lifestyle modification and pharmacotherapy are used to treat PCOS, there are few long-term outcome data regarding benefits of metabolic interventional strategies. Insulin sensitizers can improve ovulatory function, lower insulin resistance, lower androgen levels, and increase the likelihood of becoming pregnant. Further studies should yield other treatment options.
AB - Patients who have polycystic ovary syndrome (PCOS) present with infertility, recurrent miscarriages, menstrual irregularities, hirsutism, and acne. Many also have metabolic and hormonal abnormalities that can significantly increase risk for coronary artery disease, type 2 diabetes mellitus, and endometrial carcinoma. PCOS patients should be screened for obstructive sleep apnea. Early recognition may reverse physical signs of the disease, while correcting the metabolic abnormalities that can pose significant health risk if untreated. Although lifestyle modification and pharmacotherapy are used to treat PCOS, there are few long-term outcome data regarding benefits of metabolic interventional strategies. Insulin sensitizers can improve ovulatory function, lower insulin resistance, lower androgen levels, and increase the likelihood of becoming pregnant. Further studies should yield other treatment options.
UR - http://www.scopus.com/inward/record.url?scp=36549040041&partnerID=8YFLogxK
U2 - 10.1016/j.pop.2007.07.004
DO - 10.1016/j.pop.2007.07.004
M3 - Review article
C2 - 18061817
AN - SCOPUS:36549040041
SN - 0095-4543
VL - 34
SP - 761
EP - 789
JO - Primary Care - Clinics in Office Practice
JF - Primary Care - Clinics in Office Practice
IS - 4
ER -