Pleuroparenchymal fibroelastosis presenting as a hypermetabolic lung nodule

Jenny S. Machuca, Masooma Niazi, Gilda Diaz-Fuentes

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5 Scopus citations


Summary: Idiopathic pleuroparenchymal fibroelastosis is a rare, benign entity consisting of fibrotic thickening of the pleura and subpleural parenchyma due to elastic fiber proliferation. We present an elderly, male smoker with chronic obstructive airway disease and bilateral apical pleuropulmonary fibrotic changes. The computed tomogram of the chest showed a spiculated nodule in the left upper lobe and chronic fibrotic nodular changes in the right lung. A positron emission tomographic (PET) scan with 18-fluorodeoxyglucose-PET showed a hyper-metabolic nodule in the left upper lobe and uptake by the left axillary lymph nodes. Surgical resection of the nodule for presumptive malignancy showed fibro-elastosis with reactive lymph node hyperplasia. To our knowledge, this is the first reported case of nodular parenchymal fibroelastosis, with increased uptake as shown on a PET scan.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of Bronchology and Interventional Pulmonology
Issue number1
StatePublished - Jan 2011
Externally publishedYes


  • Fibroelastosis
  • Lung nodule
  • Pet scan


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