PLEKHA5: A key to unlock the blood-brain barrier?

Sylvia C. Eisele; Corey M. Gill; Ganesh M. Shankar; Priscilla K. Brastianos

doi:10.1158/1078-0432.CCR-14-2604

PLEKHA5: A key to unlock the blood-brain barrier?

Sylvia C. Eisele
, Corey M. Gill
, Ganesh M. Shankar
, Priscilla K. Brastianos

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target.

Original language	English
Pages (from-to)	1978-1980
Number of pages	3
Journal	Clinical Cancer Research
Volume	21
Issue number	9
DOIs	https://doi.org/10.1158/1078-0432.CCR-14-2604
State	Published - 1 May 2015
Externally published	Yes

Access to Document

10.1158/1078-0432.CCR-14-2604

Cite this

@article{d550b07846cd40acb4e29f32d561028e,

title = "PLEKHA5: A key to unlock the blood-brain barrier?",

abstract = "Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target.",

author = "Eisele, \{Sylvia C.\} and Gill, \{Corey M.\} and Shankar, \{Ganesh M.\} and Brastianos, \{Priscilla K.\}",

note = "Publisher Copyright: {\textcopyright} 2015 AACR.",

year = "2015",

month = may,

day = "1",

doi = "10.1158/1078-0432.CCR-14-2604",

language = "English",

volume = "21",

pages = "1978--1980",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",

number = "9",

}

TY - JOUR

T1 - PLEKHA5

T2 - A key to unlock the blood-brain barrier?

AU - Eisele, Sylvia C.

AU - Gill, Corey M.

AU - Shankar, Ganesh M.

AU - Brastianos, Priscilla K.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target.

AB - Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target.

UR - https://www.scopus.com/pages/publications/84941956063

U2 - 10.1158/1078-0432.CCR-14-2604

DO - 10.1158/1078-0432.CCR-14-2604

M3 - Article

C2 - 25779946

AN - SCOPUS:84941956063

SN - 1078-0432

VL - 21

SP - 1978

EP - 1980

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 9

ER -

PLEKHA5: A key to unlock the blood-brain barrier?

Abstract

Access to Document

Fingerprint

Cite this