Platelet Inhibitors in Coronary-Artery Bypass Operations

Helmut Gohlke, Christa Gohlke-Bärwolf, James H. Chesebro, Valentin Fuster

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: Chesebro et al. report improved graft patency with the use of platelet-inhibitor drugs before surgery (July 8 issue).1 We reported a year ago the very similar results of a prospective randomized study of the use of systemic anticoagulation started early (i.e., six hours) after surgery.2 Although our study design was somewhat different from that of Chesebro et al., we also came to the conclusion that the early use of anticoagulation was probably crucial for a beneficial effect on graft patency. In contrast to the statement of Chesebro et al. in reference to our study, we did.

Original languageEnglish
Pages (from-to)1453-1454
Number of pages2
JournalNew England Journal of Medicine
Issue number23
StatePublished - 2 Dec 1982
Externally publishedYes


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