PlateDesigner: A web-based application for the design of microplate experiments

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

In biological assays, systematic variability, known as a batch effect, can often confound the effects of true biological conditions and has been well documented for a variety of highthroughput technologies. In microplate-based multiplex experiments, such as Luminex or OLINK assays, researchers need to consider both position and plate effects. Those effects can be easily accounted for if the experiments are properly designed, which includes randomization of the samples across multiple experimental runs. However, doing the ad hoc randomization becomes challenging when handling multiple samples. PlateDesigner is the first web-based application that provides randomization for microplate experiments, ensuring that the main principles of the experimental design, such as grouping samples from the same biological units and balancing the distribution of experimental conditions, are applied. Creating randomizations with PlateDesigner is simple and the results can be exported in a variety of formats, and easily integrated with microplate readers and statistical analysis software.

Original languageEnglish
Pages (from-to)1605-1607
Number of pages3
JournalBioinformatics
Volume35
Issue number9
DOIs
StatePublished - 1 May 2019

Fingerprint

Dive into the research topics of 'PlateDesigner: A web-based application for the design of microplate experiments'. Together they form a unique fingerprint.

Cite this