Plasma factors during chronic HIV-1 infection impair IL-12 secretion by myeloid dendritic cells via a virus-independent pathway

Keyphrases

• Virus 100%
• Interleukin-12 (IL-12) 100%
• Independent Pathway 100%
• Plasma Factors 100%
• Chronic HIV Infection 100%
• Myeloid Dendritic Cells 100%
• Combined Antiretroviral Therapy (cART) 60%
• Dendritic Cell Function 60%
• Toll-like Receptors 60%
• CD4+ T Cells 40%
• Monocyte-derived DC 40%
• Cytokine Secretion 40%
• HIV Infection 20%
• Western Blot 20%
• Immune Response 20%
• T Cells 20%
• HIV Patients 20%
• Gene Expression 20%
• Quantitative PCR 20%
• Receptor-mediated 20%
• Decreased Expression 20%
• Interferon-γ 20%
• Adaptive Immune Response 20%
• T Cell Proliferation 20%
• Alleviation 20%
• Suppression Effect 20%
• Signal Transduction 20%
• Innate Immune Response 20%
• Th1 Cytokines 20%
• Opportunistic Pathogens 20%
• Plasma Donor 20%
• Transcriptional Level 20%
• Cell Dysfunction 20%
• HIV-infected Donors 20%
• Stimulatory Capacity 20%
• Circulating Factors 20%
• Polymerase Chain Reaction Array 20%
• NF-κB Signaling Pathway 20%
• Cytokine Bead Array 20%

Immunology and Microbiology

• Human Immunodeficiency Virus 1 100%
• Human Immunodeficiency Virus 100%
• Secretion (Process) 100%
• Plasma Factor 100%
• Myeloid Dendritic Cell 100%
• Blood Plasma 83%
• Human Immunodeficiency Virus Infection 50%
• Dendritic Cell Function 50%
• Cytokine 33%
• T-Helper Cell 33%
• Signal Transduction 33%
• Cytokine Release 33%
• T Cell 16%
• Western Blot 16%
• Quantitative Reverse Transcription Polymerase Chain Reaction 16%
• Infectious Agent 16%
• Immune Response 16%
• Adaptive Immune System 16%
• T Cell Proliferation 16%
• Coculture 16%
• Innate Immune System 16%