Plasma cell leukemia with myelofibrosis

T. Murayama; T. Matsui; Y. Hayashi; T. Taniguchi; M. Ito; T. Natazuka; S. Imoto; N. Iwata; T. Isobe; H. Ito; K. Chihara

doi:10.1007/BF01695697

Plasma cell leukemia with myelofibrosis

T. Murayama, T. Matsui, Y. Hayashi, T. Taniguchi, M. Ito, T. Natazuka, S. Imoto, N. Iwata, T. Isobe, H. Ito, K. Chihara

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4 Scopus citations

Abstract

We describe a case of plasma cell leukemia associated with myelofibrosis. A 60-year-old woman was admitted due to lumbago and monoclonal hypergammaglobulinemia. Peripheral blood showed about 40% of plasma-cell-like cells. A bone marrow aspiration was dry tap. The patient was diagnosed as having plasma cell leukemia with myelofibrosis by bone marrow biopsy. Plasma cell leukemia as well as myelofibrosis improved with combination chemotherapy using vincristine, pirarubicin, and dexamethasone. However, when plasma cell leukemia became resistant to chemotherapies, myelofibrosis also reappeared. This case strongly suggests the pathogenetic relationship between plasma cell leukemia and myelofibrosis.

Original language	English
Pages (from-to)	151-152
Number of pages	2
Journal	Annals of Hematology
Volume	69
Issue number	3
DOIs	https://doi.org/10.1007/BF01695697
State	Published - Sep 1994
Externally published	Yes

Keywords

Bone marrow biopsy
Myelofibrosis Chemotherapy
Plasma cell leukemia

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10.1007/BF01695697

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title = "Plasma cell leukemia with myelofibrosis",

abstract = "We describe a case of plasma cell leukemia associated with myelofibrosis. A 60-year-old woman was admitted due to lumbago and monoclonal hypergammaglobulinemia. Peripheral blood showed about 40% of plasma-cell-like cells. A bone marrow aspiration was dry tap. The patient was diagnosed as having plasma cell leukemia with myelofibrosis by bone marrow biopsy. Plasma cell leukemia as well as myelofibrosis improved with combination chemotherapy using vincristine, pirarubicin, and dexamethasone. However, when plasma cell leukemia became resistant to chemotherapies, myelofibrosis also reappeared. This case strongly suggests the pathogenetic relationship between plasma cell leukemia and myelofibrosis.",

keywords = "Bone marrow biopsy, Myelofibrosis Chemotherapy, Plasma cell leukemia",

author = "T. Murayama and T. Matsui and Y. Hayashi and T. Taniguchi and M. Ito and T. Natazuka and S. Imoto and N. Iwata and T. Isobe and H. Ito and K. Chihara",

year = "1994",

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TY - JOUR

T1 - Plasma cell leukemia with myelofibrosis

AU - Murayama, T.

AU - Matsui, T.

AU - Hayashi, Y.

AU - Taniguchi, T.

AU - Ito, M.

AU - Natazuka, T.

AU - Imoto, S.

AU - Iwata, N.

AU - Isobe, T.

AU - Ito, H.

AU - Chihara, K.

PY - 1994/9

Y1 - 1994/9

N2 - We describe a case of plasma cell leukemia associated with myelofibrosis. A 60-year-old woman was admitted due to lumbago and monoclonal hypergammaglobulinemia. Peripheral blood showed about 40% of plasma-cell-like cells. A bone marrow aspiration was dry tap. The patient was diagnosed as having plasma cell leukemia with myelofibrosis by bone marrow biopsy. Plasma cell leukemia as well as myelofibrosis improved with combination chemotherapy using vincristine, pirarubicin, and dexamethasone. However, when plasma cell leukemia became resistant to chemotherapies, myelofibrosis also reappeared. This case strongly suggests the pathogenetic relationship between plasma cell leukemia and myelofibrosis.

AB - We describe a case of plasma cell leukemia associated with myelofibrosis. A 60-year-old woman was admitted due to lumbago and monoclonal hypergammaglobulinemia. Peripheral blood showed about 40% of plasma-cell-like cells. A bone marrow aspiration was dry tap. The patient was diagnosed as having plasma cell leukemia with myelofibrosis by bone marrow biopsy. Plasma cell leukemia as well as myelofibrosis improved with combination chemotherapy using vincristine, pirarubicin, and dexamethasone. However, when plasma cell leukemia became resistant to chemotherapies, myelofibrosis also reappeared. This case strongly suggests the pathogenetic relationship between plasma cell leukemia and myelofibrosis.

KW - Bone marrow biopsy

KW - Myelofibrosis Chemotherapy

KW - Plasma cell leukemia

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JO - Annals of Hematology

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Plasma cell leukemia with myelofibrosis

Abstract

Keywords

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