Planar polarity: Converting a morphogen gradient into cellular polarity

Giovanna M. Collu; Marek Mlodzik

doi:10.1016/j.cub.2015.03.011

Planar polarity: Converting a morphogen gradient into cellular polarity

Giovanna M. Collu, Marek Mlodzik

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into cellular orientation.

Original language	English
Pages (from-to)	R372-R374
Journal	Current Biology
Volume	25
Issue number	9
DOIs	https://doi.org/10.1016/j.cub.2015.03.011
State	Published - 4 May 2015

Access to Document

10.1016/j.cub.2015.03.011

Cite this

@article{a32910625d0242e3b37efb082384fb35,

title = "Planar polarity: Converting a morphogen gradient into cellular polarity",

abstract = "Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into cellular orientation.",

author = "Collu, {Giovanna M.} and Marek Mlodzik",

year = "2015",

month = may,

day = "4",

doi = "10.1016/j.cub.2015.03.011",

language = "English",

volume = "25",

pages = "R372--R374",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "9",

}

TY - JOUR

T1 - Planar polarity

T2 - Converting a morphogen gradient into cellular polarity

AU - Collu, Giovanna M.

AU - Mlodzik, Marek

PY - 2015/5/4

Y1 - 2015/5/4

N2 - Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into cellular orientation.

AB - Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into cellular orientation.

UR - http://www.scopus.com/inward/record.url?scp=84929658556&partnerID=8YFLogxK

U2 - 10.1016/j.cub.2015.03.011

DO - 10.1016/j.cub.2015.03.011

M3 - Short survey

C2 - 25942551

AN - SCOPUS:84929658556

SN - 0960-9822

VL - 25

SP - R372-R374

JO - Current Biology

JF - Current Biology

IS - 9

ER -

Planar polarity: Converting a morphogen gradient into cellular polarity

Abstract

Access to Document

Fingerprint

Cite this